Isopropyl Alcohol

Isopropyl Alcohol

SCHEMBL1980641

CC#N.CC(C)O.CO.O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Isopropyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropyl Alcohol SCHEMBL3840021 1.00
Isopropyl Alcohol SCHEMBL333531 0.96
Isopropyl Alcohol SCHEMBL367599 0.96
Isopropyl Alcohol SCHEMBL28259581 0.92
Isopropyl Alcohol SCHEMBL3892643 0.92
Isopropylamine SCHEMBL910615 0.89 ALDH1A1 (0.40) ALDH1A1LMNATSHR
Isopropyl Alcohol SCHEMBL7065604 0.88
Isopropyl Alcohol SCHEMBL5930753 0.88 ALDH1A1 (0.46) ALDH1A1LMNATSHR
Isopropyl Alcohol SCHEMBL6009460 0.87 TSHR (0.38) ALDH1A1LMNATSHR
Isopropyl Alcohol SCHEMBL10462689 0.85 ALDH1A1 (0.43) ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117269402-B Liquid phase mass spectrum combination method for quantitatively detecting norcinnabar in human cerebrospinal fluid 中国医学科学院北京协和医院 2024-02-23 CN claimed
CN-117250301-B Liquid phase mass spectrum combined method for quantitatively detecting norcinnabar in human plasma 中国医学科学院北京协和医院 2024-02-09 CN claimed
CN-117269402-A Liquid phase mass spectrum combination method for quantitatively detecting norcinnabar in human cerebrospinal fluid 中国医学科学院北京协和医院 2023-12-22 CN claimed
CN-117250301-A Liquid phase mass spectrum combined method for quantitatively detecting norcinnabar in human plasma 中国医学科学院北京协和医院 2023-12-19 CN claimed
US-10849934-B2 Compound and preparation method thereof GUANGXI JIUFU BIOTECHNOLOGY CO., LTD (CN) 2020-12-01 US claimed
US-20200199144-A1 Compound and Preparation Method Thereof GUANGXI JIUFU BIOTECHNOLOGY CO., LTD (CN) 2020-06-25 US claimed
CN-104237407-A Method for detecting releasing rate of amantadine hydrochloride sustained release tablets SHANDONG INST PHARMACEUTICAL INDUSTRY 2014-12-24 CN claimed
US-12023407-B2 Artificial exosome composition and related methods UNIVERSITY OF MASSACHUSETTS (US) 2024-07-02 US disclosed
US-11925665-B2 Extract effective in treating drug addiction GUANGXI JIUFU BIOTECHNOLOGY CO., LTD (CN) 2024-03-12 US disclosed
CN-117269402-B Liquid phase mass spectrum combination method for quantitatively detecting norcinnabar in human cerebrospinal fluid 中国医学科学院北京协和医院 2024-02-23 CN disclosed
CN-117250301-B Liquid phase mass spectrum combined method for quantitatively detecting norcinnabar in human plasma 中国医学科学院北京协和医院 2024-02-09 CN disclosed
CN-117269402-A Liquid phase mass spectrum combination method for quantitatively detecting norcinnabar in human cerebrospinal fluid 中国医学科学院北京协和医院 2023-12-22 CN disclosed
CN-117250301-A Liquid phase mass spectrum combined method for quantitatively detecting norcinnabar in human plasma 中国医学科学院北京协和医院 2023-12-19 CN disclosed
US-20140349967-A1 NOVEL CRYSTALLINE FORMS OF TRANS-7-OXO-6-(SULPHOOXY)-1,6-DIAZABICYCLO[3,2,1]OCTANE-2-CARBOXAMIDE SODIUM SALT FOREST LABORATORIES HOLDINGS LIMITED (BM) 2014-11-27 US disclosed
US-8471025-B2 Crystalline forms of trans-7-oxo-6-(sulphooxy)-1,6-diazabicyclo[3,2,1]octane-2-carboxamide sodium salt ALLERGAN PHARMACEUTICALS INTERNATIONAL LIMITED (IE) 2013-06-25 US disclosed
US-20110152311-A1 NOVEL CRYSTALLINE FORMS OF TRANS-7-OXO-6-(SULPHOOXY)-1,6-DIAZABICYCLO[3,2,1]OCTANE-2-CARBOXAMIDE SODIUM SALT FOREST LABORATORIES HOLDINGS LTD. (BM) 2011-06-23 US disclosed
US-20090269832-A1 Growth of Microorganisms in Media Containing Crude Glycerol MODULAR GENETICS, INC. (US) 2009-10-29 US disclosed
EP-1047438-B1 A PROCESS FOR THE ISOLATION, RECOVERY AND PURIFICATION OF NON-POLAR EXTRACTIVES CA MINISTER AGRICULTURE & FOOD (CA) 2004-09-08 EP disclosed
US-6495140-B1 SOLVENT EXTRACTION OF SYNTHETIC AND PLANT EXTRACTS, SEPARATING USING POLYSACCHARIDE GEL MATRICES, THEN REGENERATING THE GELS BY WASHING FOR REUSE HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE AND AGRI-FOOD CANADA (CA) 2002-12-17 US disclosed
US-5719195-A Treatment of psoriasis with 11-cis-retinoic acid 4 THOUGHT TECHNOLOGIES (US) 1998-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152311-A1 NOVEL CRYSTALLINE FORMS OF TRANS-7-OXO-6-(SULPHOOXY)-1,6-DIAZABICYCLO[3,2,1]OCTANE-2-CARBOXAMIDE SODIUM SALT SLC10A6, SLC5A2, SLC5A1 ALDH1A1 4203/4885LMNA 3412/4885TSHR 772/4885
US-11925665-B2 Extract effective in treating drug addiction NR1H3, CYP46A1, GRIN3A ALDH1A1 317/4885LMNA 4446/4885TSHR 2294/4885
US-20200199144-A1 Compound and Preparation Method Thereof CYP2E1, CYP1A2, CYP4X1 ALDH1A1 132/4885LMNA 958/4885TSHR 3537/4885
US-20140349967-A1 NOVEL CRYSTALLINE FORMS OF TRANS-7-OXO-6-(SULPHOOXY)-1,6-DIAZABICYCLO[3,2,1]OCTANE-2-CARBOXAMIDE SODIUM SALT SLC10A6, SLC5A2, SLC5A1 ALDH1A1 4203/4885LMNA 3412/4885TSHR 772/4885
US-10849934-B2 Compound and preparation method thereof CYP2E1, CYP1A2, CYP4X1 ALDH1A1 132/4885LMNA 958/4885TSHR 3537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.