SCHEMBL198246

SCHEMBL198246

CCCCC/C=C\C/C=C\CCCCCCCCO[C@H]1CC[C@@H](CN(C)C)C[C@H]1OCCCCCCCC/C=C\C/C=C\CCCCC

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200528 1.00 FAAH (0.38) FAAHALDH1A1CNR1CNR2
SCHEMBL221563 0.92 ALDH1A1 (0.40) ALDH1A1CNR1CNR2
SCHEMBL19525638 0.92 ALDH1A1 (0.40) ALDH1A1CNR1CNR2
SCHEMBL199145 0.92 ALDH1A1 (0.40) ALDH1A1CNR1CNR2
SCHEMBL2621135 0.88 FAAH (0.37) FAAHALDH1A1CNR1CNR2
SCHEMBL131121 0.87 FAAH (0.41) FAAHALDH1A1CNR1CNR2
SCHEMBL131114 0.87 FAAH (0.41) FAAHALDH1A1CNR1CNR2
SCHEMBL19525549 0.83 FAAH (0.43) FAAHALDH1A1CNR1CNR2
SCHEMBL198291 0.82 ALDH1A1 (0.39) ALDH1A1CNR1CNR2
SCHEMBL25863262 0.82 ALDH1A1 (0.39) ALDH1A1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11771715-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-10-03 US disclosed
US-11766449-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-09-26 US disclosed
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-11679120-B2 Circular RNA compositions and methods ORNA THERAPEUTICS, INC. (US) 2023-06-20 US disclosed
US-20230058784-A1 CIRCULAR RNA COMPOSITIONS AND METHODS ORNA THERAPEUTICS, INC. 2023-02-23 US disclosed
EP-2512449-B1 METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS UNIV BRITISH COLUMBIA (CA) 2019-08-07 EP disclosed
US-20160317676-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2016-11-03 US disclosed
US-8722082-B2 Lipids and compositions for the delivery of therapeutics TEKMIRA PHARMACEUTICALS CORPORATION (CA) 2014-05-13 US disclosed
US-20130017223-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-01-17 US disclosed
US-20120058144-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ALNYLAM PHARMACEUTICALS, INC. (US) 2012-03-08 US disclosed
WO-2010054384-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ALNYLAM PHARMACEUTICALS, INC. (US) 2010-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11771715-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB FAAH 4833/4885ALDH1A1 4484/4885CNR1 4579/4885
US-20130017223-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS LIPA, APOB, LIPC FAAH 1523/4885ALDH1A1 4338/4885CNR1 3995/4885
US-20120058144-A1 LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS ABCB4, CETP, SGMS1 FAAH 1360/4885ALDH1A1 3777/4885CNR1 2763/4885
US-20230226096-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, HNRNPA1, HNRNPAB FAAH 4833/4885ALDH1A1 4484/4885CNR1 4579/4885
US-20160317676-A1 METHODS AND COMPOSITIONS FOR DELIVERY OF NUCLEIC ACIDS LIPA, APOB, LIPC FAAH 1523/4885ALDH1A1 4338/4885CNR1 3995/4885
US-20230058784-A1 CIRCULAR RNA COMPOSITIONS AND METHODS RTCB, RNGTT, HNRNPAB FAAH 4846/4885ALDH1A1 4532/4885CNR1 4492/4885
US-11679120-B2 Circular RNA compositions and methods RTCB, HNRNPA1, HNRNPAB FAAH 4833/4885ALDH1A1 4484/4885CNR1 4579/4885
US-11766449-B2 Circular RNA compositions and methods RTCB, RNGTT, HNRNPAB FAAH 4846/4885ALDH1A1 4532/4885CNR1 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.