Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18763535 | 0.84 | LMNA (0.42) | GPR55ESR1ESR2GRM2ALDH1A1 | |
| SCHEMBL23758353 | 0.83 | CYP3A4 (0.36) | ESR1ESR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL21076611 | 0.77 | ESR1 (0.37) | ESR1ESR2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL22895111 | 0.77 | NR3C2 (0.41) | ESR1ESR2ALDH1A1 | |
| SCHEMBL21076444 | 0.76 | ESR1 (0.42) | GPR55ESR1ESR2GRM2 | |
| SCHEMBL25489183 | 0.74 | CYP2A6 (0.36) | SMN1; SMN2CYP11B2NPC1RAB9A | |
| SCHEMBL30144069 | 0.74 | CYP2A6 (0.36) | SMN1; SMN2CYP11B2NPC1RAB9A | |
| SCHEMBL3513409 | 0.74 | CYP2A6 (0.36) | SMN1; SMN2CYP11B2NPC1RAB9A | |
| SCHEMBL19998188 | 0.73 | ALDH1A1 (0.37) | ESR1ESR2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL12120613 | 0.72 | GABRA1 (0.33) | ESR1PRMT5WDR77RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180030059-A1 | COELENTERAZINE ANALOGUES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2018-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030059-A1 | COELENTERAZINE ANALOGUES | GLB1, SI, TCF7L2 | GPR55 455/4885ESR1 4444/4885ESR2 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.