Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20442226 | 0.98 | CYP1A2 (0.39) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL21210844 | 0.98 | CYP1A2 (0.39) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL18842935 | 0.98 | CYP1A2 (0.39) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20214851 | 0.98 | CYP1A2 (0.39) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20008446 | 0.98 | CYP1A2 (0.39) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL21164225 | 0.82 | CYP1A2 (0.38) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20008796 | 0.78 | CYP2C9 (0.40) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20210119 | 0.75 | CTSK (0.37) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL18583188 | 0.74 | CYP2C9 (0.34) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL25543688 | 0.72 | LMNA (0.37) | CYP1A2CYP19A1CYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570153-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-10544151-B2 | Compounds and uses thereof | KALA PHARMACEUTICALS, INC. (US) | 2020-01-28 | — | — | US | disclosed |
| US-10244756-B2 | Fungicidal N-cycloalkyl-N-{[ortho-(1-substituted-cycloalkyl)heteroaryl]methyl}(thio)carboxamides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-02 | — | — | US | disclosed |
| US-20190023710-A1 | NOVEL COMPOUNDS AND USES THEREOF | KALA BIO, Inc. | 2019-01-24 | — | — | US | disclosed |
| US-20180146670-A1 | FUNGICIDAL N-CYCLOALKYL-N-{[ORTHO-(1-SUBSTITUTED-CYCLOALKYL)HETEROARYL]METHYL}(THIO)CARBOXAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-31 | — | — | US | disclosed |
| US-20180037572-A1 | UREA DERIVATIVES AND USES THEREOF | KALA BIO, Inc. | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023710-A1 | NOVEL COMPOUNDS AND USES THEREOF | RB1, VEGFA, UACA | CYP1A2 3822/4885CYP19A1 927/4885CYP2C9 2170/4885 |
| US-20180037572-A1 | UREA DERIVATIVES AND USES THEREOF | UACA, RB1, FLT1 | CYP1A2 3517/4885CYP19A1 1286/4885CYP2C9 1643/4885 |
| US-10570153-B2 | Benzodiazepine derivatives as RSV inhibitors | GABRA5, GABRA1, GABBR2 | CYP1A2 58/4885CYP19A1 473/4885CYP2C9 62/4885 |
| US-20180146670-A1 | FUNGICIDAL N-CYCLOALKYL-N-{[ORTHO-(1-SUBSTITUTED-CYCLOALKYL)HETEROARYL]METHYL}(THIO)CARBOXAMIDES | CBR3, CBR1, CYP51A1 | CYP1A2 9/4885CYP19A1 366/4885CYP2C9 32/4885 |
| US-10544151-B2 | Compounds and uses thereof | RB1, VEGFA, KDR | CYP1A2 3863/4885CYP19A1 886/4885CYP2C9 2088/4885 |
| US-10244756-B2 | Fungicidal N-cycloalkyl-N-{[ortho-(1-substituted-cycloalkyl)heteroaryl]methyl}(thio)carboxamides | CBR3, CBR1, CYP51A1 | CYP1A2 9/4885CYP19A1 366/4885CYP2C9 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.