Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 14/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.49 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2162496 | 0.87 | ALDH1A1 (0.58) | — | |
| SCHEMBL19860105 | 0.78 | PRMT3 (0.62) | PRMT3NOTUMIMPDH2 | |
| SCHEMBL19860085 | 0.76 | TERT (0.64) | PRMT3IMPDH2 | |
| SCHEMBL19860124 | 0.76 | IMPDH2 (0.59) | PRMT3NOTUMIMPDH2 | |
| SCHEMBL19860074 | 0.75 | TERT (0.63) | PRMT3IMPDH2 | |
| SCHEMBL14642082 | 0.75 | ROCK2 (0.52) | PRMT3IMPDH2 | |
| SCHEMBL25005902 | 0.74 | POLB (0.54) | — | |
| SCHEMBL2162616 | 0.74 | IMPDH2 (0.70) | PRMT3NOTUMIMPDH2 | |
| SCHEMBL19860095 | 0.74 | IMPDH2 (0.62) | PRMT3NOTUMIMPDH2 | |
| SCHEMBL19860084 | 0.74 | IMPDH2 (0.55) | PRMT3NOTUMIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890123-B2 | 6-aminoisoquinoline compounds | AERIE PHARMACEUTICALS, INC. (US) | 2018-02-13 | — | — | US | disclosed |