SCHEMBL19862779

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16386582	1.00	PTGES (0.41)	PTGESALOX5KIF11TACR1CYP19A1
	SCHEMBL2068610	0.95	PTGES (0.38)	PTGESALOX5KIF11TACR1CYP19A1
	SCHEMBL27608014	0.95	TACR1 (0.39)	PTGESALOX5KIF11TACR1CYP19A1
	SCHEMBL28588395	0.93	PTAFR (0.39)	PTGESALOX5KIF11TACR1PTAFR
	SCHEMBL22079981	0.88	PTGES (0.44)	PTGESALOX5KIF11CYP19A1PTAFR
	SCHEMBL22079658	0.88	PTGES (0.44)	PTGESALOX5KIF11CYP19A1PTAFR
	SCHEMBL26625120	0.87	TACR1 (0.34)	PTGESALOX5TACR1PTAFRS1PR1
	SCHEMBL6660571	0.86	RAB9A (0.41)	PTGESALOX5PTAFRS1PR1TP53
	SCHEMBL19934075	0.86	KIF11 (0.39)	PTGESALOX5KIF11TACR1PTAFR
	SCHEMBL15038424	0.86	ALDH1A1 (0.39)	SMN1; SMN2RAB9ANPC1ALDH1A1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.