SCHEMBL19863142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19863136	0.95	GSTP1 (0.34)	ESR1ESR2HSD17B1HSD17B2TUBB4A
	SCHEMBL23775682	0.90	GSTP1 (0.32)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL23776013	0.89	HSD17B1 (0.32)	HSD17B1HSD17B2CYP1A2CYP3A4CYP2D6
	SCHEMBL23775774	0.88	HSD17B1 (0.31)	HSD17B1HSD17B2TUBB4ATUBBTUBA3C
	SCHEMBL23775773	0.87	HSD17B1 (0.31)	HSD17B1HSD17B2CYP1A2CYP3A4CYP2D6
	SCHEMBL22707556	0.85	PIM1 (0.33)	HSD17B1HSD17B2TUBB4ATUBBTUBA3C
	SCHEMBL20857791	0.84	GSTP1 (0.39)	ESR1ESR2HSD17B1HSD17B2TUBB4A
	SCHEMBL22707997	0.82	ALOX5 (0.33)	ALOX5CYP1A2ALDH1A1
	SCHEMBL22708010	0.82	HDAC4 (0.35)	HSD17B1HSD17B2TUBB4ATUBBTUBA3C
	SCHEMBL20857778	0.81	HSD17B10 (0.35)	ESR1ESR2HSP90AA1IDO1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.