SCHEMBL20857791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20857779	0.93	ALDH1A1 (0.36)	GSTP1GPR84CYP1A1CYP1B1CYP1A2
	SCHEMBL20857939	0.87	RET (0.31)	—
	SCHEMBL23775682	0.84	GSTP1 (0.32)	GSTP1HDAC4HDAC2HDAC8GPR84
	SCHEMBL20857893	0.84	GPR84 (0.36)	GSTP1HSD17B1HSD17B2HDAC4HDAC2
	SCHEMBL19863142	0.84	ESR1 (0.36)	GSTP1HSD17B1HSD17B2HDAC4HDAC2
	SCHEMBL20857932	0.84	HSD17B10 (0.39)	KDM4E
	SCHEMBL20858026	0.84	HSD17B10 (0.41)	KDM4EALOX5
	SCHEMBL19863136	0.84	GSTP1 (0.34)	GSTP1HSD17B1HSD17B2HDAC4HDAC2
	SCHEMBL22568582	0.83	KDM4E (0.32)	KDM4E
	SCHEMBL25459727	0.82	KDM4E (0.37)	KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.