Sugi Predict

Sugi Predict / Compounds / SCHEMBL19909418

SCHEMBL19909418

SCHEMBL19909418

Cc1ccccc1-c1ccc2c3ccc(-c4ccccc4C)cc3n(-c3cc(-c4ccncc4)cc(-n4c5cc(-c6ccccc6C)ccc5c5ccc(-c6ccccc6C)cc54)c3C#N)c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ABL1 P00519 2/20 0.39
▸ AR P10275 1/20 0.38
▸ PIP4K2A P48426 1/20 0.37
▸ MAP4K4 O95819 1/20 0.36
▸ SQOR Q9Y6N5 1/20 0.36
▸ TGFBR1 P36897 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ ALOX15 P16050 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ CYP11B1 P15538 1/20 0.34
▸ CYP11B2 P19099 1/20 0.34
▸ HPGD P15428 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ LMNA P02545 2/20 0.34
▸ TP53 P04637 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19909421 0.97 ABL1 (0.38) ABL1ARPIP4K2AMAP4K4SQOR
SCHEMBL19908897 0.91 AR (0.38) ABL1ARPIP4K2AMAP4K4SQOR
SCHEMBL19908923 0.90 SQOR (0.36) ABL1ARPIP4K2AMAP4K4SQOR
SCHEMBL20620028 0.88 CYP11B2 (0.44) ABL1PIP4K2ASQORALDH1A1CYP11B1
SCHEMBL19909057 0.88 ABL1 (0.39) ABL1MAP4K4SQORALDH1A1CYP11B1
SCHEMBL19909055 0.87 ABL1 (0.36) ABL1SQORALDH1A1CYP11B2TDP1
SCHEMBL19909435 0.87 AR (0.38) ABL1ARPIP4K2AALDH1A1HSD17B10
SCHEMBL19919541 0.87 PDE10A (0.41) TGFBR1ALDH1A1HSD17B10HPGDLMNA
SCHEMBL21414215 0.86 AR (0.39) ABL1ARPIP4K2AALDH1A1CYP11B1
SCHEMBL19909112 0.86 ADORA1 (0.42) SQORCLK4LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11588114-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-02-21 — — US disclosed
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2020-07-02 — — US disclosed
US-10665792-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2020-05-26 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 — — US disclosed
EP-3287451-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200212316-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, OR51E2 ABL1 2890/4885AR 4245/4885PIP4K2A 3805/4885
US-10665792-B2 Organic molecules for use in optoelectronic devices OR10J3, CFD, AOX1 ABL1 2221/4885AR 4444/4885PIP4K2A 4543/4885
US-11588114-B2 Organic molecules for use in optoelectronic devices OR10J3, OPRM1, OR51E2 ABL1 2890/4885AR 4245/4885PIP4K2A 3805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.