SCHEMBL1992255

SCHEMBL1992255

O=COc1c(F)cccc1F

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.40
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
NFE2L2 Q16236 3/20 0.33
BCHE P06276 1/20 0.33
KMT2A Q03164 2/20 0.33
SLC2A1 P11166 1/20 0.33
SLC2A4 P14672 1/20 0.33
SLC6A2 P23975 1/20 0.32
IKBKB O14920 1/20 0.31
ALB P02768 1/20 0.31
KRAS P01116 1/20 0.31
MEN1 O00255 1/20 0.31
RAB9A P51151 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PKM P14618 1/20 0.30
PKLR P30613 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16545836 0.85 KMT2A (0.40) ERN1KMT2ASLC6A2MEN1ALDH1A1
SCHEMBL24207668 0.80 RAB9A (0.34) ERN1KMT2AMEN1RAB9AALDH1A1
SCHEMBL6442207 0.80 ALB (0.52) CES2CES1BCHEALBRAB9A
SCHEMBL1997466 0.78 CES2 (0.38) ERN1CES2CES1
SCHEMBL1547886 0.75 NFE2L2 (0.36) ERN1CES2CES1NFE2L2KMT2A
SCHEMBL3182645 0.75 ERN1 (0.40) ERN1CES2CES1
SCHEMBL23386909 0.75 NFE2L2 (0.33) ERN1CES2CES1NFE2L2SLC6A2
SCHEMBL1992172 0.75 SLC6A2 (0.43) ERN1CES2CES1NFE2L2BCHE
SCHEMBL95849 0.73 NFE2L2 (0.39) NFE2L2ALDH1A1TDP1
SCHEMBL28366367 0.73 SLC6A2 (0.42) ERN1CES2CES1NFE2L2BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-0354297-B1 THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-08-05 EP claimed
US-9645467-B2 Electrophoretic particles, electrophoretic dispersion liquid, display sheet, display device, and electronic equipment SEIKO EPSON CORPORATION (JP) 2017-05-09 US disclosed
WO-2017053864-A1 CYSTEINE PROTEASE INHIBITORS INTRACELLULAR TECHNOLOGIES, LLC (US) 2017-03-30 WO disclosed
US-9608287-B2 Non-aqueous electrolytic solution, electrical storage device utilizing same, and cyclic sulfonic acid ester compound UBE INDUSTRIES, LTD. (JP) 2017-03-28 US disclosed
EP-2701230-B1 NON-AQUEOUS ELECTROLYTE SOLUTION, ELECTRICITY STORAGE DEVICE USING THE SAME, AND TRIFLUOROMETHYLBENZENE COMPOUND UBE INDUSTRIES (JP) 2016-11-23 EP disclosed
US-9472828-B2 Nonaqueous electrolyte solution, electricity storage device using same, and trifluoromethylbenzene compound UBE INDUSTRIES, LTD. (JP) 2016-10-18 US disclosed
EP-2719688-B1 Process for producing tetrazolyloxime derivatives NIPPON SODA CO (JP) 2016-07-20 EP disclosed
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed
EP-2719686-B1 Process to halogenate a picoline derivative NIPPON SODA CO (JP) 2015-12-02 EP disclosed
EP-2719687-B1 Process to make a bromopicoline derivative NIPPON SODA CO (JP) 2015-09-16 EP disclosed
EP-2546236-A1 COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE Nippon Soda Co., Ltd. (JP) 2013-01-16 EP disclosed
US-20130012713-A1 COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE NIPPON SODA CO., LTD 2013-01-10 US disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed
EP-0354297-B1 THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-08-05 EP disclosed
US-5021412-A Protecting agricultural crops MITSUI TOATSU CHEMICALS, INC. (JP) 1991-06-04 US disclosed
EP-0354297-A1 Thiadiazines, process for production thereof, and insecticidal and acaricidal agents comprising the thiadiazines MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 ERN1 96/4885CES2 83/4885CES1 624/4885
US-20130012713-A1 COMPOUND CONTAINING PYRIDINE RING AND METHOD FOR PRODUCING HALOGENATED PICOLINE DERIVATIVE AND TETRAZOLYLOXIME DERIVATIVE CBR3, PNPO, AADAC ERN1 3014/4885CES2 388/4885CES1 1493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.