SCHEMBL19923746

SCHEMBL19923746

CC1C(=O)N([Si](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)N1[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.35
LOX P28300 1/20 0.33
LOXL3 P58215 1/20 0.33
LOXL4 Q96JB6 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
MAOA P21397 1/20 0.31
SMO Q99835 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923447 0.83 KMT2A (0.34) GRM4LOXLOXL3LOXL4LOXL2
SCHEMBL19923679 0.81 LOX (0.39) LOXLOXL3LOXL4LOXL2MAOA
SCHEMBL19923550 0.80 GRM4 (0.47) GRM4LOXLOXL3LOXL4LOXL2
SCHEMBL19923702 0.80 CES2 (0.34)
SCHEMBL19923602 0.79 SMO (0.37) SMO
SCHEMBL19923455 0.78 MMP2 (0.33)
SCHEMBL19923769 0.76 SMO (0.53) SMO
SCHEMBL19923763 0.74 BRD4 (0.38)
SCHEMBL19923495 0.69 CES2 (0.33)
SCHEMBL19923533 0.68 GRM4 (0.34) GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN GRM4 2257/4885LOX 551/4885LOXL3 2027/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM GRM4 2114/4885LOX 660/4885LOXL3 2218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.