SCHEMBL19923698

SCHEMBL19923698

CC(C)N1C(=O)N([Si](C)(C)C)C(=O)C1c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 6/20 0.34
GRM4 Q14833 1/20 0.33
ALDH1A1 P00352 3/20 0.33
GFER P55789 1/20 0.33
TSHR P16473 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
HPGD P15428 1/20 0.31
GRM5 P41594 1/20 0.31
BRD4 O60885 1/20 0.31
LMNA P02545 2/20 0.31
USP2 O75604 1/20 0.31
ADORA3 P0DMS8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19923533 0.86 GRM4 (0.34) MMP2GRM4ALDH1A1GFERTSHR
SCHEMBL19923443 0.84 LMNA (0.34) MMP2GRM4ALDH1A1GFERKMT2A
SCHEMBL19923598 0.82 SMN1; SMN2 (0.34) MMP2GRM4ALDH1A1GFERKMT2A
SCHEMBL19923726 0.79 ALDH1A1 (0.43) MMP2ALDH1A1GFERKMT2ARAB9A
SCHEMBL19923690 0.79 MMP2 (0.36) MMP2ALDH1A1GFERTSHRKMT2A
SCHEMBL19923468 0.79 LMNA (0.41) MMP2ALDH1A1GFERTSHRKMT2A
SCHEMBL19923792 0.79 MMP2 (0.36) MMP2GRM4ALDH1A1TSHRKMT2A
SCHEMBL17791223 0.76 LMNA (0.47) MMP2ALDH1A1KMT2ARAB9ALMNA
SCHEMBL19923669 0.75 LMNA (0.40) MMP2ALDH1A1TSHRKMT2AHPGD
SCHEMBL19923481 0.73 EHMT2 (0.49) ALDH1A1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US claimed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US claimed
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds BRIDGESTONE CORPORATION (JP) 2021-01-26 US disclosed
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS BRIDGESTONE CORPORATION (JP) 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180065935-A1 POLYMERS FUNCTIONALIZED WITH N-PROTECTED HYDANTOIN COMPOUNDS PARG, HNMT, PARN MMP2 1092/4885GRM4 2257/4885ALDH1A1 2648/4885
US-10899718-B2 Polymers functionalized with N-protected hydantoin compounds HNMT, PARG, PAM MMP2 1416/4885GRM4 2114/4885ALDH1A1 2554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.