Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574427 | 0.87 | ALDH1A1 (0.47) | PLA2G4AALDH1A1CES1FDPSTSHR | |
| SCHEMBL11156307 | 0.84 | PLA2G4A (0.48) | PLA2G4ACES1 | |
| SCHEMBL2657137 | 0.84 | PLA2G4A (0.44) | PLA2G4AALDH1A1CES1FDPSTSHR | |
| SCHEMBL7174088 | 0.83 | CES1 (0.49) | PLA2G4ACES1 | |
| SCHEMBL2656867 | 0.83 | CES1 (0.46) | PLA2G4AALDH1A1CES1FDPSTSHR | |
| SCHEMBL6179956 | 0.79 | SMN1; SMN2 (0.44) | PLA2G4AALDH1A1CES1FDPSPKM | |
| SCHEMBL28152645 | 0.78 | TSHR (0.45) | ALDH1A1FDPSTSHRPKMCYP3A4 | |
| Urea SCHEMBL7180010 | 0.78 | PLA2G4A (0.45) | PLA2G4AALDH1A1FDPSPKMHRH2 | |
| SCHEMBL4759129 | 0.77 | — | — | |
| SCHEMBL244221 | 0.76 | PLA2G4A (0.41) | PLA2G4AALDH1A1FDPSHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066015-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | WASHINGTON UNIVERSITY (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066015-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | HDGF, MMP7, HGF | PLA2G4A 1750/4885ALDH1A1 2862/4885CES1 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.