Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930458 | 0.89 | SLC6A7 (0.54) | ALDH1A1KDM4ESLC6A7SMN1; SMN2LMNA | |
| SCHEMBL19930448 | 0.87 | SLC6A7 (0.55) | ALDH1A1KDM4ESLC6A7SMN1; SMN2TSHR | |
| SCHEMBL19930457 | 0.83 | HSD17B10 (0.62) | ALDH1A1PKMKDM4ESMN1; SMN2TSHR | |
| SCHEMBL18126737 | 0.82 | ALDH1A1 (0.58) | ALDH1A1PKMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL19930453 | 0.81 | ENPP2 (0.58) | ALDH1A1KDM4ESMN1; SMN2GRM5 | |
| SCHEMBL19930446 | 0.81 | HSD17B10 (0.63) | ALDH1A1KDM4ESMN1; SMN2CA12CA1 | |
| SCHEMBL19930459 | 0.78 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19930449 | 0.77 | DPP4 (0.49) | ALDH1A1NPSR1HPGD | |
| SCHEMBL10726894 | 0.76 | PKM (0.74) | ALDH1A1PKMKDM4EHTTSMN1; SMN2 | |
| SCHEMBL19930456 | 0.75 | ALDH1A1 (0.44) | ALDH1A1KDM4EHTTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064711-A1 | METHODS FOR TREATING CRYPTOSPORIDIOSIS USING TRIAZOLOPYRIDAZINES | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064711-A1 | METHODS FOR TREATING CRYPTOSPORIDIOSIS USING TRIAZOLOPYRIDAZINES | CLPP, SI, SAMHD1 | ALDH1A1 1257/4885PKM 1349/4885KDM4E 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.