Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 10/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 4/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16561105 | 1.00 | STING1 (0.57) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL1331888 | 1.00 | STING1 (0.57) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL30847445 | 0.92 | STING1 (0.54) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL18744137 | 0.88 | LMNA (0.50) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL13176571 | 0.88 | LMNA (0.50) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL17826621 | 0.85 | LMNA (0.47) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL18720751 | 0.83 | LMNA (0.47) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL18742090 | 0.81 | LMNA (0.43) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL17826618 | 0.78 | LMNA (0.45) | STING1PDE3BPDE3ALMNARAPGEF3 | |
| SCHEMBL29359340 | 0.78 | STING1 (0.56) | STING1PDE3BPDE3ALMNARAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11819550-B2 | Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) | EAGLE BIOLOGICS, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| US-20210038718-A1 | Liquid Protein Formulations Containing Organophosphates | EAGLE BIOLOGICS, INC. | 2021-02-11 | — | — | US | disclosed |
| US-10821184-B2 | Liquid protein formulations containing thiamine pyrophosphate (TPP) | EAGLE BIOLOGICS, INC. (US) | 2020-11-03 | — | — | US | disclosed |
| US-20180153997-A1 | Liquid Protein Formulations Containing Organophosphates | EAGLE BIOLOGICS, INC. | 2018-06-07 | — | — | US | disclosed |
| US-9913905-B2 | Liquid pharmaceutical formulations for injection comprising thiamine pyrophosphate 1-(3-aminopropyl)-2-methyl-1H-imidazole and uses thereof | EAGLE BIOLOGICS, INC. (US) | 2018-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11819550-B2 | Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) | PDE7A, PDE8A, PDE8B | STING1 234/4885PDE3B 69/4885PDE3A 53/4885 |
| US-10821184-B2 | Liquid protein formulations containing thiamine pyrophosphate (TPP) | PLPBP, ITPA, PLTP | STING1 1077/4885PDE3B 2469/4885PDE3A 1837/4885 |
| US-20210038718-A1 | Liquid Protein Formulations Containing Organophosphates | IGFBP1, IGFBP5, IGF2BP1 | STING1 680/4885PDE3B 1219/4885PDE3A 697/4885 |
| US-20180153997-A1 | Liquid Protein Formulations Containing Organophosphates | IGFBP1, IGFBP5, IGF2BP1 | STING1 680/4885PDE3B 1219/4885PDE3A 697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.