Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19928510 | 0.80 | CYP4F2 (0.34) | ALDH1A1CYP1A2CYP3A4GAACYP4F2 | |
| SCHEMBL22312167 | 0.75 | CCR9 (0.35) | ALDH1A1L3MBTL1SMN1; SMN2MAPK1NPC1 | |
| SCHEMBL22313139 | 0.72 | NUDT1 (0.31) | ALDH1A1NUDT1SMN1; SMN2LMNA | |
| SCHEMBL18855007 | 0.69 | CNR2 (0.43) | ALDH1A1CYP1A2CYP3A4GAANUDT1 | |
| SCHEMBL16976879 | 0.68 | CYP1A2 (0.50) | ALDH1A1CYP1A2NUDT1TSHRPIK3CA | |
| SCHEMBL18363110 | 0.67 | CYP4F2 (0.55) | ALDH1A1CYP1A2CYP3A4GAACYP4F2 | |
| SCHEMBL20669564 | 0.67 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP3A4GAAABCB11 | |
| SCHEMBL22312163 | 0.66 | LMNA (0.40) | ALDH1A1TSHRL3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL24369218 | 0.65 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP3A4GAAABCB11 | |
| SCHEMBL24023322 | 0.65 | HSD11B1 (0.39) | ALDH1A1GAASMN1; SMN2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10280142-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072672-A1 | BIPYRIDYL COMPOUND | CBR1, NR0B2, ERBB2 | ALDH1A1 1501/4885CYP1A2 133/4885CYP3A4 236/4885 |
| US-10280142-B2 | Bipyridyl compound | CBR1, NR0B2, ERBB2 | ALDH1A1 1501/4885CYP1A2 133/4885CYP3A4 236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.