Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313139 | 0.76 | NUDT1 (0.31) | LMNASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19965015 | 0.75 | ALDH1A1 (0.33) | LMNASMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL22289552 | 0.74 | DGAT1 (0.45) | CCR9 | |
| SCHEMBL22312163 | 0.69 | LMNA (0.40) | LMNASMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL30908540 | 0.69 | ALDH1A1 (0.38) | CCR9ALDH1A1NPC1RAB9A | |
| SCHEMBL30908504 | 0.68 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1HSD17B10MAPK1 | |
| SCHEMBL17961930 | 0.66 | GRIN2D (0.41) | CCR9LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL24359978 | 0.66 | ALDH1A1 (0.45) | LMNASMN1; SMN2HTTALDH1A1NPC1 | |
| SCHEMBL28738078 | 0.66 | KDM4E (0.51) | LMNASMN1; SMN2HTTALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL3679217 | 0.65 | ALDH1A1 (0.47) | CCR9HTTALDH1A1MEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020159889-A1 | SREBP INHIBITORS COMPRISING A THIOPHENE CENTRAL RING | CAPULUS THERAPEUTICS, LLC (US) | 2020-08-06 | — | — | WO | disclosed |