Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | SORD | Q00796 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1992434 | 0.83 | GSK3B (0.48) | GAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL1992433 | 0.83 | GSK3B (0.48) | GAAKMT2ASMN1; SMN2MAPT | |
| SCHEMBL4556640 | 0.81 | CHRNA7 (0.34) | HDAC11HDAC6GAAKMT2ALMNA | |
| SCHEMBL1989631 | 0.75 | GRIN2D (0.46) | GAAKMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17957759 | 0.73 | HDAC6 (0.63) | HDAC11HDAC6LMNASMN1; SMN2TSHR | |
| SCHEMBL1990714 | 0.73 | ALDH1A1 (0.40) | HDAC11GAAKMT2AALDH1A1LMNA | |
| SCHEMBL17957800 | 0.72 | LMNA (0.48) | HDAC11HDAC6GAAKMT2AALDH1A1 | |
| SCHEMBL21047659 | 0.69 | CRBN (0.52) | HDAC11HDAC6GAAKMT2ALMNA | |
| SCHEMBL21979404 | 0.68 | ELANE (0.63) | GAAKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL29533076 | 0.68 | GPR119 (0.50) | ALDH1A1SMN1; SMN2MAPTELANEFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8263587-B2 | Benzoxazepine compounds, their preparation and use | PIRAMAL HEALTHCARE LIMITED (IN) | 2012-09-11 | — | — | US | disclosed |
| EP-2077846-B1 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LTD (IN) | 2011-10-12 | — | — | EP | disclosed |
| US-20110152247-A1 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Enterprises Limited (IN) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152247-A1 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | GPR119, INSR, SLC5A1 | HDAC11 432/4885HDAC6 2241/4885GAA 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.