Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | SORD | Q00796 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997107 | 0.81 | HDAC11 (0.41) | CHRNA7HTR3AHDAC11FAAHGAA | |
| SCHEMBL1992434 | 0.80 | GSK3B (0.48) | GAAKMT2ASMN1; SMN2 | |
| SCHEMBL1992433 | 0.80 | GSK3B (0.48) | GAAKMT2ASMN1; SMN2 | |
| SCHEMBL1990714 | 0.68 | ALDH1A1 (0.40) | HDAC11GAAKMT2ALMNATSHR | |
| SCHEMBL17957800 | 0.67 | LMNA (0.48) | HDAC11GAAKMT2AHDAC6LMNA | |
| SCHEMBL17957759 | 0.66 | HDAC6 (0.63) | HDAC11HDAC6LMNATSHRTP53 | |
| SCHEMBL496869 | 0.63 | CYP3A4 (0.49) | KMT2ALMNATSHRTP53 | |
| SCHEMBL21979404 | 0.62 | ELANE (0.63) | CHRNA7HTR3AFAAHGAAKMT2A | |
| SCHEMBL195554 | 0.61 | HTR6 (0.53) | CHRNA7HTR3AGAAKMT2ALMNA | |
| SCHEMBL2056153 | 0.61 | GAA (0.58) | CHRNA7HTR3AGAAKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2077846-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Life Sciences Limited (IN) | 2009-07-15 | — | — | EP | claimed |
| WO-2008053446-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2008-05-08 | — | — | WO | claimed |
| EP-2077846-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | Piramal Life Sciences Limited (IN) | 2009-07-15 | — | — | EP | disclosed |
| WO-2008053446-A2 | BENZOXAZEPINE COMPOUNDS, THEIR PREPARATION AND USE | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2008-05-08 | — | — | WO | disclosed |