Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HTR6 | P50406 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16618849 | 0.81 | KMT2A (0.56) | HSD17B10PLK1HDAC1TSHRKDM4E | |
| SCHEMBL19971392 | 0.79 | POLB (0.38) | TSHRCHRNB4CHRNA3 | |
| SCHEMBL19971360 | 0.79 | AKR1C3 (0.56) | HSD17B10PLK1HDAC1HTR6KDM4E | |
| SCHEMBL16619142 | 0.78 | HTR6 (0.42) | HTR6IDE | |
| SCHEMBL16618784 | 0.77 | HTR6 (0.43) | HDAC1HTR6KDM4EIDEAKR1C3 | |
| SCHEMBL16618966 | 0.75 | KDM4E (0.45) | HDAC1HTR6KDM4EHDAC2HDAC11 | |
| SCHEMBL16626068 | 0.74 | HTR6 (0.36) | HDAC1HTR6KDM4EALPLIDE | |
| SCHEMBL19971346 | 0.74 | IDE (0.41) | HSD17B10PLK1HDAC1HTR6IDE | |
| SCHEMBL16619044 | 0.74 | HTR6 (0.45) | HDAC1HTR6HDAC2HDAC6IDE | |
| SCHEMBL2472672 | 0.73 | NAMPT (0.43) | HSD17B10HDAC1TSHRKDM4EIDE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | claimed |