Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21273278 | 0.84 | LMNA (0.42) | SMN1; SMN2 | |
| SCHEMBL21381142 | 0.81 | HRH3 (0.38) | CCR5MLYCDOGAHTTSMN1; SMN2 | |
| SCHEMBL28305432 | 0.80 | OGA (0.30) | OGAHTTSMN1; SMN2 | |
| SCHEMBL12810893 | 0.80 | CCR5 (0.36) | CCR5MLYCDOGAHTTSMN1; SMN2 | |
| SCHEMBL19975384 | 0.80 | MLYCD (0.38) | CCR5MLYCDOGAHTTSMN1; SMN2 | |
| SCHEMBL12810894 | 0.75 | ALDH1A1 (0.47) | CCR5OGAHTTSMN1; SMN2UBE2M | |
| SCHEMBL21273270 | 0.73 | PDE10A (0.31) | — | |
| SCHEMBL19975224 | 0.73 | — | — | |
| SCHEMBL19975223 | 0.73 | GPR119 (0.34) | CCR5MLYCDOGAHTTSMN1; SMN2 | |
| SCHEMBL986413 | 0.72 | UBE2M (0.38) | MLYCDHTTUBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512845-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018053157-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2018-03-22 | — | — | WO | disclosed |