SCHEMBL296383

SCHEMBL296383

O=S(=O)(Br)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 3/20 0.58
ALDH1A1 P00352 4/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
TSHR P16473 2/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA12 O43570 1/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
PLA2G7 Q13093 1/20 0.52
CA9 Q16790 1/20 0.52
CA13 Q8N1Q1 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
DUSP3 P51452 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779850 0.89 HTR6 (0.70) HTR6ALDH1A1CA1CA2TSHR
SCHEMBL8779885 0.83 CA2 (0.41) HTR6ALDH1A1CA1CA2TSHR
SCHEMBL11854546 0.82 TDP1 (0.43) HTR6ALDH1A1CA1CA2TSHR
SCHEMBL1067859 0.82 ALDH1A1 (0.67) HTR6ALDH1A1CA1CA2TSHR
SCHEMBL10451410 0.79 CA1 (0.55) HTR6ALDH1A1CA1CA2TSHR
SCHEMBL8779845 0.78 MMP13 (0.51) HTR6ALDH1A1CA1CA2CA12
SCHEMBL6259956 0.76 HTR6 (0.50) HTR6ALDH1A1CA1CA2TSHR
SCHEMBL19975469 0.75 CA2 (0.52) ALDH1A1CA1CA2CA12CA9
Disulfone SCHEMBL493732 0.73 HTR6 (0.65) HTR6ALDH1A1CA1CA2TSHR
Disulfone SCHEMBL8427811 0.73 HTR6 (0.65) HTR6ALDH1A1CA1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350611-B Organic electrolyte and preparation method thereof, electrolyte membrane layer and preparation method thereof, lithium ion solid-state battery and vehicle 重庆长安汽车股份有限公司 2026-05-12 CN claimed
EP-4644366-A1 PREPARATION METHODS FOR PILOCARPINE AND INTERMEDIATE COMPOUND THEREOF Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) 2025-11-05 EP claimed
US-20250296923-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND VALO HEALTH, INC. (US) 2025-09-25 US claimed
CN-119630643-A Process and intermediate compounds for the preparation of 6-substituted-1- (2H) -isoquinolinones 瓦洛健康公司 2025-03-14 CN claimed
CN-116199607-B Preparation method of pilocarpine and intermediate compound thereof 浙江奥翔药业股份有限公司 2025-02-14 CN claimed
CN-119350611-A Organic electrolyte and preparation method thereof, electrolyte membrane layer and preparation method thereof, lithium ion solid-state battery and vehicle 重庆长安汽车股份有限公司 2025-01-24 CN claimed
EP-3247703-B1 IMPROVED PROCESS FOR PREPARING STATIN PRECURSOR CENTRIENT PHARMACEUTICALS NETHERLANDS B V (NL) 2024-10-16 EP claimed
US-20240287031-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND VALO HEALTH, INC. (US) 2024-08-29 US claimed
EP-4402129-A1 <SMALLCAPS/>? ? ?H? ? ? ? ?PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND Valo Health, Inc. (US) 2024-07-24 EP claimed
US-20240228425-A1 PREPARATION METHOD OF PILOCARPINE AND ITS INTERMEDIATE COMPOUNDS ZHEJIANG AUSUN PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US claimed
US-5973216-A Method for producing bromomethylcyclopropane KURARAY CO., LTD. (JP) 1999-10-26 US claimed
EP-0612740-B1 Methods of producing pantothenic acid derivative and its starting materials for producing the same FUJIREBIO KK (JP) 1999-09-22 EP claimed
US-5719298-A REACTING PANTOTHENIC ACID ACETONIDE WITH UREA COMPOUND IN THE PRESENCE OF ACYLATING AGENT FUJIREBIO INC. (JP) 1998-02-17 US claimed
EP-0557519-B1 PROCESS FOR PREPARING SULFONAMIDE DERIVATIVE OF NORBORNANE SHIONOGI & CO (JP) 1997-06-04 EP claimed
US-5384419-A Preparation process for 20-keto-21(S) hydroxy steroid compounds and intermediates ROUSSEL-UCLAF (FR) 1995-01-24 US claimed
EP-0612740-A1 Methods of producing pantothenic acid derivative and its starting materials for producing the same FUJIREBIO Inc. (JP) 1994-08-31 EP claimed
EP-0557519-A1 PROCESS FOR PREPARING SULFONAMIDE DERIVATIVE OF NORBORNANE SHIONOGI & CO., LTD. (JP) 1993-09-01 EP claimed
US-5124462-A PREPARATION OF NORBORNYL SULFONAMIDE DERIVATIVES SHIONGI & CO., LTD. (JP) 1992-06-23 US claimed
US-4386935-A Process for producing discharge reserve prints on textile materials with amino-azo-benzene dyes CASSELLA AKTIENGESELLSCHAFT (DE) 1983-06-07 US claimed
US-4127580-A MULTISTAGE PARCOR (FR) 1978-11-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287031-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND ROCK1, ROCK2, CIT HTR6 3378/4885ALDH1A1 1653/4885CA1 3050/4885
US-20250296923-A1 PROCESS FOR PREPARING 6-SUBSTITUTED-1-(2H)-ISOQUINOLINONES AND INTERMEDIATE COMPOUND ROCK1, ROCK2, CIT HTR6 3378/4885ALDH1A1 1653/4885CA1 3050/4885
US-20240228425-A1 PREPARATION METHOD OF PILOCARPINE AND ITS INTERMEDIATE COMPOUNDS CYP4B1, CYP4A11, CYP3A4 HTR6 1220/4885ALDH1A1 134/4885CA1 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.