Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNG | P07510 | 1/20 | 0.31 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976766 | 0.85 | ABL1 (0.43) | LMNAABL1BCRMAPK1DYRK1A | |
| SCHEMBL16752857 | 0.84 | CHRNA1 (0.34) | JAK2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL16752855 | 0.84 | CHRNA1 (0.34) | JAK2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL19976857 | 0.83 | MAPK1 (0.35) | LMNAABL1BCRMAPK1DYRK1A | |
| SCHEMBL19976758 | 0.80 | DYRK1A (0.40) | LMNAABL1BCRMAPK1ALPL | |
| SCHEMBL19976846 | 0.80 | KDM4E (0.42) | ABL1BCRMAPK1DYRK1AKDM4E | |
| SCHEMBL19976781 | 0.80 | TRPA1 (0.35) | LMNAABL1BCRMAPK1DYRK1A | |
| SCHEMBL18558606 | 0.80 | LMNA (0.40) | LMNAIDO1ABL1BCRMAPK1 | |
| SCHEMBL19976866 | 0.80 | DYRK1A (0.42) | MAPK1DYRK1AJAK3NTRK1 | |
| SCHEMBL18558419 | 0.79 | LMNA (0.36) | LMNAMAPK1ALPLDYRK1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |