Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 8/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.35 |
| ▸ | CDK2 | P24941 | 3/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.35 |
| ▸ | FLT4 | P35916 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | CLK2 | P49760 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | MARK3 | P27448 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976781 | 0.90 | TRPA1 (0.35) | MAPK1LMNADYRK1AKDM4EHTT | |
| SCHEMBL19976846 | 0.88 | KDM4E (0.42) | MAPK1DYRK1ACDK2CDK1FLT4 | |
| SCHEMBL19976785 | 0.88 | MAPK1 (0.38) | MAPK1DYRK1ACDK2CDK1FLT4 | |
| SCHEMBL19976766 | 0.85 | ABL1 (0.43) | MAPK1LMNADYRK1ACDK2CDK1 | |
| SCHEMBL19976768 | 0.84 | MAPK1 (0.38) | MAPK1DYRK1ACDK2CDK1FLT4 | |
| SCHEMBL19976801 | 0.84 | TRPA1 (0.37) | MAPK1DYRK1ACDK2CDK1FLT4 | |
| SCHEMBL19976780 | 0.83 | LMNA (0.33) | MAPK1LMNADYRK1AKDM4EHTT | |
| SCHEMBL19976866 | 0.83 | DYRK1A (0.42) | MAPK1DYRK1ACDK2CDK1FLT4 | |
| SCHEMBL19976776 | 0.83 | GSK3B (0.48) | MAPK1DYRK1AGSK3BTRPA1HDAC6 | |
| SCHEMBL19976805 | 0.83 | ALDH1A1 (0.36) | MAPK1LMNADYRK1ACDK2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |