Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.32 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976851 | 0.94 | POLB (0.35) | MAPK1TRPA1PDE2AHTTKDM4E | |
| SCHEMBL19976798 | 0.93 | PTGES (0.36) | MAPK1KDM4EPOLBKMT2AALDH1A1 | |
| SCHEMBL19976928 | 0.91 | CTNNB1 (0.37) | MAPK1HTTKDM4EPOLBKMT2A | |
| SCHEMBL19976727 | 0.91 | GSK3B (0.36) | MAPK1TRPA1PDE2AHTTKMT2A | |
| SCHEMBL19976784 | 0.90 | MAPK1 (0.38) | MAPK1POLBMAP2K4NAMPT | |
| SCHEMBL19976777 | 0.88 | POLB (0.39) | MAPK1POLBKMT2AHPGDLMNA | |
| SCHEMBL16752809 | 0.85 | GSK3B (0.48) | MAPK1TRPA1GSK3BMAP2K4MAPK6 | |
| SCHEMBL16752808 | 0.85 | GSK3B (0.48) | MAPK1TRPA1GSK3BMAP2K4MAPK6 | |
| SCHEMBL16752811 | 0.85 | GSK3B (0.48) | MAPK1TRPA1GSK3BMAP2K4MAPK6 | |
| SCHEMBL19976737 | 0.84 | HPGD (0.35) | MAPK1HTTKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |