Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PDE6D | O43924 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE6A | P16499 | 1/20 | 0.32 |
| ▸ | PDE6G | P18545 | 1/20 | 0.32 |
| ▸ | PDE6B | P35913 | 1/20 | 0.32 |
| ▸ | PDE6C | P51160 | 1/20 | 0.32 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976944 | 0.93 | MAPK1 (0.36) | MAPK1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL19976728 | 0.91 | PTGES (0.37) | PTGESMAPK1HDAC6MAPTMEN1 | |
| SCHEMBL19976928 | 0.91 | CTNNB1 (0.37) | PTGESMAPK1LMNAKMT2AKDM4E | |
| SCHEMBL19976851 | 0.87 | POLB (0.35) | MAPK1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL19976727 | 0.84 | GSK3B (0.36) | PTGESMAPK1HDAC6LMNAMAPT | |
| SCHEMBL19976784 | 0.83 | MAPK1 (0.38) | MAPK1DGAT2POLB | |
| SCHEMBL19976803 | 0.81 | MAPK1 (0.38) | MAPK1DGAT2LMNAKDM4EALDH1A1 | |
| SCHEMBL9921021 | 0.81 | LMNA (0.37) | MAPK1DGAT2HDAC6LMNAMAPT | |
| SCHEMBL19976833 | 0.81 | HPGD (0.41) | MAPK1DGAT2LMNAMAPTKDM4E | |
| SCHEMBL19976777 | 0.81 | POLB (0.39) | MAPK1DGAT2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |