Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976968 | 0.89 | KCNMA1 (0.57) | KCNMA1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL19976911 | 0.88 | LMNA (0.54) | KCNMA1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL19976943 | 0.88 | KMT2A (0.48) | LMNAMEN1KMT2AMAPTPOLB | |
| SCHEMBL19977067 | 0.85 | CRHBP (0.60) | KCNMA1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL19976906 | 0.85 | PGR (0.52) | LMNAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL19976953 | 0.83 | LMNA (0.56) | KCNMA1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL16999807 | 0.83 | PSMB5 (0.56) | KCNMA1LMNANPSR1L3MBTL1 | |
| SCHEMBL16999829 | 0.83 | PSMB5 (0.56) | KCNMA1LMNANPSR1L3MBTL1 | |
| SCHEMBL16993918 | 0.83 | PSMB5 (0.56) | KCNMA1LMNANPSR1L3MBTL1 | |
| SCHEMBL16999332 | 0.83 | PSMB5 (0.56) | KCNMA1LMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |