Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977070 | 0.91 | KCNK3 (0.48) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19977138 | 0.90 | HPGD (0.48) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL16999510 | 0.84 | USP30 (0.54) | L3MBTL1 | |
| SCHEMBL19977069 | 0.83 | ALDH1A1 (0.57) | HPGDLMNAMAPTSMN1; SMN2KCNK3 | |
| SCHEMBL19976955 | 0.82 | POLB (0.53) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19977072 | 0.80 | LMNA (0.54) | HPGDLMNAGAASMN1; SMN2KCNK3 | |
| SCHEMBL19977018 | 0.80 | SMN1; SMN2 (0.50) | HPGDLMNAGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL19976970 | 0.78 | NPC1 (0.53) | HPGDLMNAMAPTSMN1; SMN2KCNK3 | |
| SCHEMBL19977071 | 0.78 | LMNA (0.45) | HPGDLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL19976922 | 0.78 | HPGD (0.66) | PGRSCN1ASCN2ASCN3AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |