Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | CCKAR | P32238 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977028 | 0.86 | LMNA (0.47) | DHPSLMNAMAPTNPC1GAA | |
| SCHEMBL19976913 | 0.86 | LMNA (0.43) | DHPSLMNAMAPTHPGDNPC1 | |
| SCHEMBL19976905 | 0.86 | KMT2A (0.56) | DHPSMAPTNPC1ALDH1A1MEN1 | |
| SCHEMBL19977090 | 0.83 | DHPS (0.46) | DHPSPARP1LMNAKDM4EHTT | |
| SCHEMBL16999621 | 0.83 | HPGDS (0.48) | KDM4EHDAC1HDAC3CCKARMEN1 | |
| SCHEMBL19976985 | 0.83 | TRPV1 (0.52) | DHPSLMNAHPGDNPC1ALDH1A1 | |
| SCHEMBL19976994 | 0.81 | PGR (0.57) | PGRSCN1ASCN2ASCN3ALMNA | |
| SCHEMBL19977014 | 0.81 | ADRB1 (0.49) | DHPSLMNAHPGDMAPK1HSD17B10 | |
| SCHEMBL19977126 | 0.80 | MRGPRX1 (0.44) | DHPSLMNAHPGDNPC1KDM4E | |
| SCHEMBL19976992 | 0.80 | TRPV1 (0.48) | LMNAHTTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |