Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 known ✓ | P08235 | 3/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898991 | 0.84 | ALDH1A1 (0.41) | GPR84CYP1A2CYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL27746631 | 0.82 | ALDH1A1 (0.40) | CYP1A2CYP2C19ALDH1A1CYP3A4ALOX15 | |
| Lithium Ion SCHEMBL4623871 | 0.73 | GPR84 (0.46) | GPR84ALDH1A1CYP3A4TDP1NR3C2 | |
| SCHEMBL1995047 | 0.73 | GPR84 (0.50) | GPR84ALDH1A1CYP3A4TDP1NR3C2 | |
| Potassium Ion SCHEMBL1996218 | 0.71 | GPR84 (0.40) | GPR84CYP3A4ALOX15ALOX12TSHR | |
| SCHEMBL8623383 | 0.69 | CYP3A4 (0.76) | CYP1A2CYP2C19ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL28716953 | 0.69 | CNR1 (0.49) | CYP2C19ALDH1A1CYP3A4ALOX15ALOX12 | |
| SCHEMBL1262667 | 0.68 | MEN1 (0.64) | CYP1A2ALDH1A1CYP3A4ALOX15ALOX12 | |
| SCHEMBL6939817 | 0.67 | MAPT (0.50) | ALDH1A1CYP3A4ALOX15ALOX12HPGD | |
| SCHEMBL6854492 | 0.67 | ESR1 (0.61) | ALDH1A1CYP3A4ALOX15HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4474426-A1 | POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED OBJECT | Kaneka Corporation (JP) | 2024-12-11 | — | — | EP | disclosed |
| CN-118574893-A | Polycarbonate resin composition and molded article | 株式会社钟化 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023234367-A1 | POLYCARBONATE RESIN COMPOSITION AND SHAPED ARTICLE | 株式会社カネカ | 2023-12-07 | — | — | WO | disclosed |
| WO-2023149409-A1 | POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED OBJECT | 株式会社カネカ | 2023-08-10 | — | — | WO | disclosed |
| EP-3056488-A1 | BISBENZOXAZINONE COMPOUND | Teijin Chemicals, Ltd. (JP) | 2016-08-17 | — | — | EP | disclosed |
| EP-2505585-B1 | BIS-BENZOXAZINONE COMPOUND | TEIJIN CHEMICALS LTD (JP) | 2016-08-03 | — | — | EP | disclosed |
| US-8969436-B2 | Method of producing a molded article | TEIJIN CHEMICALS, LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8697788-B2 | Polycarbonate resin composition and molded article thereof | TEIJIN CHEMICALS, LTD. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-20120252941-A1 | BISBENZOXAZINONE COMPOUND | TEIJIN CHEMICALS, LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-2505585-A1 | BIS-BENZOXAZINONE COMPOUND | Teijin Chemicals, Ltd. (JP) | 2012-10-03 | — | — | EP | disclosed |
| US-20050119441-A1 | Copolycarbonate and heat-resistant part comprising the copolymer | TEIJIN CHEMICALS LTD. (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1038920-B1 | RESIN COMPOSITION | TEIJIN CHEMICALS LTD (JP) | 2004-12-15 | — | — | EP | disclosed |
| US-6780917-B2 | MOLDING MATERIALS; MIXTURE CONTAINING FILLER | TEIJIN CHEMICALS, LTD. (JP) | 2004-08-24 | — | — | US | disclosed |
| US-20040152806-A1 | Polycarbonate resin composition, pellets thereof and molded article thereof | TEIJIN CHEMICALS LTD. (JP) | 2004-08-05 | — | — | US | disclosed |
| US-20040014851-A1 | Polycarbonate-based molding material and optical disk substrates | TEIJIN CHEMICALS LTD. (JP) | 2004-01-22 | — | — | US | disclosed |
| EP-1300445-A1 | AROMATIC POLYCARBONATE RESIN COMPOSITION | Teijin Chemicals, Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |
| US-20030004251-A1 | Aromatic polycarbonate resin composition | TEIJIN CHEMICALS LTD. (JP) | 2003-01-02 | — | — | US | disclosed |
| US-6362269-B1 | BLEND OF AROMATIC POLYCARBONATE AND STYRENE POLYMER OR AROMATIC POLYESTER | TEIJIN CHEMICALS, LTD. (JP) | 2002-03-26 | — | — | US | disclosed |
| US-6355767-B1 | BLEND WITH THERMOPLASTIC GRAFT POLYMER COMPRISING VINYL CYANIDE, VINYLAROMATIC AND DIENE COMONOMERS; HEAT RESISTANCE, TRANSPARENCY, NONHYDROLYZING, IMPACT STRENGTH | TEIJIN CHEMICALS, LTD (JP) | 2002-03-12 | — | — | US | disclosed |
| EP-1038920-A1 | RESIN COMPOSITION | Teijin Chemicals, Ltd. (JP) | 2000-09-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252941-A1 | BISBENZOXAZINONE COMPOUND | RPS4Y1, RPS4X, H1-4 | NR3C2 350/4885GPR84 2802/4885CYP1A2 847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.