Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 known ✓ | Q92731 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL4623871 | 0.97 | GPR84 (0.46) | GPR84MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9332956 | 0.84 | CYP3A4 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL1548707 | 0.82 | CYP3A4 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL6472688 | 0.82 | CYP3A4 (0.48) | MEN1KMT2ASMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL402058 | 0.82 | GPR84 (0.47) | GPR84SMN1; SMN2ALDH1A1CYP3A4POLB | |
| SCHEMBL8659995 | 0.82 | GPR84 (0.47) | GPR84SMN1; SMN2ALDH1A1CYP3A4POLB | |
| SCHEMBL1900143 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL5077474 | 0.81 | SRC (0.62) | MEN1KMT2ASMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL11508054 | 0.81 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2ALDH1A1ESR1 | |
| SCHEMBL218852 | 0.80 | CYP3A4 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4474426-A1 | POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED OBJECT | Kaneka Corporation (JP) | 2024-12-11 | — | — | EP | disclosed |
| CN-118574893-A | Polycarbonate resin composition and molded article | 株式会社钟化 | 2024-08-30 | — | — | CN | disclosed |
| WO-2023234367-A1 | POLYCARBONATE RESIN COMPOSITION AND SHAPED ARTICLE | 株式会社カネカ | 2023-12-07 | — | — | WO | disclosed |
| WO-2023149409-A1 | POLYCARBONATE-BASED RESIN COMPOSITION AND MOLDED OBJECT | 株式会社カネカ | 2023-08-10 | — | — | WO | disclosed |
| EP-2883925-B1 | Polypropylene based composition | REPSOL SA (ES) | 2016-10-05 | — | — | EP | disclosed |
| EP-2883925-A1 | Polypropylene based composition | Repsol, S.A. (ES) | 2015-06-17 | — | — | EP | disclosed |
| US-8969436-B2 | Method of producing a molded article | TEIJIN CHEMICALS, LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-8697788-B2 | Polycarbonate resin composition and molded article thereof | TEIJIN CHEMICALS, LTD. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-20120252941-A1 | BISBENZOXAZINONE COMPOUND | TEIJIN CHEMICALS, LTD. (JP) | 2012-10-04 | — | — | US | disclosed |
| US-20120095141-A1 | POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | TEIJIN CHEMICALS, LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-6300415-B1 | MOLDABILITY, MOLD SHRINKAGE FACTOR ON MOLDING, RIGIDITY, FLEXIBILITY, IMPACT RESISTANCE, IN PARTICULAR LOW-TEMPERATURE IMPACT RESISTANCE, TRANSPARENCY, GLOSS, STRESS-WHITENING RESISTANCE | CHISSO CORPORATION (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-0885926-B1 | Propylene polymer blends, processes of producing the same, and polypropylene resin compositions | CHISSO CORP (JP) | 2001-03-21 | — | — | EP | disclosed |
| EP-1038920-A1 | RESIN COMPOSITION | Teijin Chemicals, Ltd. (JP) | 2000-09-27 | — | — | EP | disclosed |
| EP-1022308-A1 | POLYPROPYLENE COMPOSITION | CHISSO CORPORATION (JP) | 2000-07-26 | — | — | EP | disclosed |
| EP-1002809-A1 | PROPYLENE/ETHYLENE RANDOM COPOLYMER, MOLDING MATERIAL, AND MOLDED ARTICLE | CHISSO CORPORATION (JP) | 2000-05-24 | — | — | EP | disclosed |
| EP-0790262-B1 | PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF | CHISSO CORP (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-6005034-A | POLYMER MELTS OF ETHYLENE-PROPYLENE COPOLYMERS | CHISSO CORPOATION (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885926-A2 | Propylene polymer blends, processes of producing the same, and polypropylene resin compositions | CHISSO CORPORATION (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0863183-A1 | PROPYLENE COMPOSITION, PROCESS FOR PREPARING THE SAME, POLYPROPYLENE COMPOSITION, AND MOLDED ARTICLES | CHISSO CORPORATION (JP) | 1998-09-09 | — | — | EP | disclosed |
| EP-0790262-A1 | PROPYLENE-ETHYLENE COPOLYMER COMPOSITIONS AND PROCESS FOR THE PRODUCTION THEREOF | CHISSO CORPORATION (JP) | 1997-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252941-A1 | BISBENZOXAZINONE COMPOUND | RPS4Y1, RPS4X, H1-4 | ESR2 3150/4885GPR84 2802/4885MEN1 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.