Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAP3K8 | P41279 | 6/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983733 | 0.90 | SLC6A2 (0.37) | CYP11B1CYP11B2MAOASRCMAPT | |
| SCHEMBL19984127 | 0.88 | NUDT1 (0.36) | CYP11B1CYP11B2MAOAMAP3K8EGFR | |
| SCHEMBL19983850 | 0.87 | LRRK2 (0.40) | SRCMAP3K8LRRK2SLC6A4 | |
| SCHEMBL19983727 | 0.85 | ABL1 (0.36) | KDM4EALDH1A1LMNAMAPTSLC6A2 | |
| SCHEMBL19983883 | 0.84 | HTR2C (0.32) | EGFRSLC6A2SLC6A4 | |
| SCHEMBL19984171 | 0.83 | POLB (0.37) | MAPK14EGFRKDM4EALDH1A1SLC6A2 | |
| SCHEMBL19984087 | 0.83 | SLC6A2 (0.34) | MAP3K8MAPK13EIF2AK2MAPK12MAPK11 | |
| SCHEMBL19984177 | 0.81 | HTR2C (0.39) | ALDH1A1 | |
| SCHEMBL19983721 | 0.81 | HTR2C (0.32) | MAPT | |
| SCHEMBL16626425 | 0.80 | HTR6 (0.39) | CYP11B1CYP11B2MAOASRCMAP3K8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |