Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.30 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983733 | 0.90 | SLC6A2 (0.37) | SRCCNR2SLC6A4 | |
| SCHEMBL19984171 | 0.88 | POLB (0.37) | SLC6A3BCL6 | |
| SCHEMBL19983883 | 0.88 | HTR2C (0.32) | SLC6A4BCL6 | |
| SCHEMBL19983740 | 0.87 | CYP11B1 (0.35) | LRRK2SRCSLC6A4MAP3K8 | |
| SCHEMBL19983736 | 0.85 | MAPT (0.38) | ABCG2BCL6 | |
| SCHEMBL19984135 | 0.84 | BCL6 (0.40) | SRCCNR2ABCG2BCL6 | |
| SCHEMBL19983743 | 0.83 | SRC (0.40) | PDE5ASRCSLC6A4 | |
| SCHEMBL19984127 | 0.83 | NUDT1 (0.36) | KCNH2SLC6A4MAP3K8 | |
| SCHEMBL19984087 | 0.83 | SLC6A2 (0.34) | SLC6A4MAP3K8 | |
| SCHEMBL19983727 | 0.82 | ABL1 (0.36) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |