Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.40 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983733 | 0.87 | SLC6A2 (0.37) | CNR2MAPTSRCCYP11B1CYP11B2 | |
| SCHEMBL19984171 | 0.85 | POLB (0.37) | BCL6KDM4EALDH1A1EGFR | |
| SCHEMBL19983883 | 0.85 | HTR2C (0.32) | BCL6BCOREGFR | |
| SCHEMBL19983850 | 0.84 | LRRK2 (0.40) | BCL6CNR2ABCG2SRC | |
| SCHEMBL19983743 | 0.84 | SRC (0.40) | SRCALPL | |
| SCHEMBL19983736 | 0.83 | MAPT (0.38) | BCL6BCORKDM4EMAPTABCG2 | |
| SCHEMBL16626434 | 0.82 | PDE4A (0.40) | BCL6BCORCSNK2A1CNR2BUB1 | |
| Hydrochloric Acid SCHEMBL16619061 | 0.81 | PDE4A (0.40) | BCL6BCORCSNK2A1CNR2BUB1 | |
| SCHEMBL19984127 | 0.80 | NUDT1 (0.36) | CYP11B1CYP11B2EGFR | |
| SCHEMBL19984087 | 0.80 | SLC6A2 (0.34) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |