Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984015 | 0.87 | GRM4 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19983890 | 0.87 | EGFR (0.43) | KMT2AGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19984142 | 0.87 | BACE1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19983769 | 0.84 | TRPV1 (0.44) | GRM4 | |
| SCHEMBL19983892 | 0.84 | PTGS2 (0.46) | KDM4EALDH1A1GRM4CHRNB2CHRNA7 | |
| SCHEMBL19983904 | 0.81 | GRM4 (0.45) | LMNAMAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL19983863 | 0.81 | GPR84 (0.38) | KDM4EALDH1A1GRM4CHRNB2CHRNA7 | |
| SCHEMBL19984195 | 0.79 | LRRK2 (0.41) | KMT2AKDM4EALDH1A1MEN1GRM4 | |
| SCHEMBL19984000 | 0.77 | HTR2A (0.46) | MAPTKMT2AKDM4EALDH1A1ALOX12 | |
| SCHEMBL19984193 | 0.77 | GPR84 (0.37) | NPC1RAB9AGRM4CHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |