Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983828 | 0.87 | LMNA (0.38) | CHRNB2CHRNA7CHRNA4GABRPGABRD | |
| SCHEMBL19984015 | 0.86 | GRM4 (0.39) | CHRNB2CHRNA7CHRNA4GABRPGABRD | |
| SCHEMBL19984142 | 0.86 | BACE1 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19983769 | 0.84 | TRPV1 (0.44) | GRM4 | |
| SCHEMBL19983892 | 0.81 | PTGS2 (0.46) | CHRNB2CHRNA7CHRNA4GRM4GPR84 | |
| SCHEMBL19983863 | 0.80 | GPR84 (0.38) | CHRNB2CHRNA7CHRNA4GRM4GPR84 | |
| SCHEMBL19983904 | 0.80 | GRM4 (0.45) | EGFRGRM4POLBKMT2A | |
| SCHEMBL19984195 | 0.78 | LRRK2 (0.41) | CHRNB2CHRNA7CHRNA4GRM4KMT2A | |
| SCHEMBL19984002 | 0.77 | CHRNB2 (0.51) | EGFRERBB2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983728 | 0.76 | CHRNB2 (0.39) | CHRNB2CHRNA7CHRNA4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |