Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | YAP1 | P46937 | 1/20 | 0.31 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.31 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984279 | 0.91 | SLC6A4 (0.35) | HTR2ASLC6A4KCNH2YAP1LMNA | |
| SCHEMBL19984163 | 0.89 | FADS1 (0.36) | MAPTHTR2ASLC6A4KCNH2MPO | |
| SCHEMBL19983775 | 0.88 | EGFR (0.34) | BRAFEGFR | |
| SCHEMBL19983937 | 0.86 | MPO (0.37) | APPMAPTHTR2ASLC6A4KCNH2 | |
| SCHEMBL19984021 | 0.86 | GAK (0.40) | APPHTR2ASLC6A4KCNH2DHODH | |
| SCHEMBL19984212 | 0.84 | SLC6A4 (0.33) | MAPTTP53SMN1; SMN2HTR2ASLC6A4 | |
| SCHEMBL19983888 | 0.82 | P2RX7 (0.31) | SLC6A4KCNH2 | |
| SCHEMBL19984022 | 0.82 | AKR1C3 (0.38) | APPMAPTAKR1C3AKR1C2 | |
| SCHEMBL19984250 | 0.81 | HTR2A (0.30) | HTR2ASLC6A4KCNH2 | |
| SCHEMBL19983909 | 0.81 | SLC6A2 (0.35) | HTR2ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |