Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983934 | 0.81 | TUBB1 (0.41) | TUBB1MAPTALDH1A1L3MBTL1NR4A2 | |
| SCHEMBL19984304 | 0.80 | NR4A2 (0.38) | TUBB1NR4A2NPC1RAB9AMAPK14 | |
| SCHEMBL19983834 | 0.78 | PRKAG1 (0.42) | TUBB1MAPTPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL19984228 | 0.75 | NR4A2 (0.46) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL19983830 | 0.75 | HTR2A (0.48) | MAPTALDH1A1MEN1KMT2AMAPK14 | |
| SCHEMBL19983975 | 0.74 | ALK (0.40) | NR4A2MEN1KMT2AMAPK14 | |
| SCHEMBL25229260 | 0.70 | MAPT (0.63) | TUBB1MAPTALDH1A1L3MBTL1NR4A2 | |
| SCHEMBL1003506 | 0.70 | CPS1 (0.58) | MAPTALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL30523138 | 0.69 | MAPT (0.57) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL31501108 | 0.69 | NR4A2 (0.78) | TUBB1MAPTALDH1A1L3MBTL1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |