Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAG1 | P54619 | 4/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 1/20 | 0.36 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983975 | 0.87 | ALK (0.40) | NR4A2ALKMEN1KMT2ABCL6 | |
| SCHEMBL19984228 | 0.78 | NR4A2 (0.46) | PRKAG1PRKAA1PRKAB1NR4A2ALK | |
| SCHEMBL19983947 | 0.78 | TUBB1 (0.48) | PRKAG1PRKAA1PRKAB1NR4A2MAPT | |
| SCHEMBL16626544 | 0.76 | GPR84 (0.36) | PRKAG1PRKAA1PRKAB1MEN1KMT2A | |
| SCHEMBL19984050 | 0.75 | CYP1A2 (0.42) | PRKAG1PRKAA1PRKAB1MEN1KMT2A | |
| SCHEMBL19983934 | 0.74 | TUBB1 (0.41) | NR4A2MAPTTUBB1ROCK2ROCK1 | |
| SCHEMBL19984304 | 0.74 | NR4A2 (0.38) | NR4A2TUBB1IMPDH2RAB9A | |
| SCHEMBL16618626 | 0.70 | HDAC1 (0.40) | SYKMEN1KMT2AHDAC1HDAC2 | |
| SCHEMBL20060890 | 0.70 | POLB (0.47) | PRKAG1PRKAA1PRKAB1MAPTTUBB1 | |
| SCHEMBL19984057 | 0.69 | AKR1C3 (0.35) | MAPTMEN1KMT2ALRRK2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |