Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 4/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | BCL6 | P41182 | 3/20 | 0.35 |
| ▸ | BCOR | Q6W2J9 | 3/20 | 0.35 |
| ▸ | HAT1 | O14929 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 6/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983834 | 0.87 | PRKAG1 (0.42) | ALKNR4A2BCL6BCORMEN1 | |
| SCHEMBL19984228 | 0.83 | NR4A2 (0.46) | ALKNR4A2BCL6BCORHAT1 | |
| SCHEMBL19984304 | 0.78 | NR4A2 (0.38) | NR4A2HAT1EP300MAPK14 | |
| SCHEMBL19983947 | 0.74 | TUBB1 (0.48) | NR4A2MAPK14MEN1KMT2A | |
| SCHEMBL19983934 | 0.70 | TUBB1 (0.41) | NR4A2 | |
| SCHEMBL16619336 | 0.69 | HDAC1 (0.42) | ALKPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5425587 | 0.67 | EGFR (0.47) | MEN1KMT2A | |
| SCHEMBL30762247 | 0.67 | ALDH1A1 (0.51) | NR4A2 | |
| SCHEMBL15651984 | 0.65 | NR4A2 (0.41) | NR4A2HAT1EP300MEN1KMT2A | |
| SCHEMBL19983894 | 0.65 | GPR84 (0.39) | MAPK8MAPK10MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |