Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.36 |
| ▸ | HAT1 | O14929 | 4/20 | 0.35 |
| ▸ | EP300 | Q09472 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984228 | 0.80 | NR4A2 (0.46) | NR4A2HAT1EP300MAPK14DHODH | |
| SCHEMBL19983947 | 0.80 | TUBB1 (0.48) | NR4A2MAPK14TUBB1NPC1RAB9A | |
| SCHEMBL19983975 | 0.78 | ALK (0.40) | NR4A2HAT1EP300MAPK14 | |
| SCHEMBL19983834 | 0.74 | PRKAG1 (0.42) | NR4A2TUBB1IMPDH2RAB9A | |
| SCHEMBL19983934 | 0.74 | TUBB1 (0.41) | NR4A2STING1IDO1TDO2TUBB1 | |
| SCHEMBL19983751 | 0.74 | GPR84 (0.40) | STING1CFTR | |
| SCHEMBL7847121 | 0.70 | CDK4 (0.46) | HAT1EP300TDO2TUBB1NPC1 | |
| SCHEMBL30762247 | 0.69 | ALDH1A1 (0.51) | NR4A2TUBB1IMPDH2 | |
| SCHEMBL15651984 | 0.67 | NR4A2 (0.41) | NR4A2HAT1EP300TUBB1 | |
| SCHEMBL207031 | 0.66 | KDM4E (0.57) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |