Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.46 |
| ▸ | BCL6 | P41182 | 3/20 | 0.41 |
| ▸ | BCOR | Q6W2J9 | 3/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HAT1 | O14929 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983975 | 0.83 | ALK (0.40) | NR4A2BCL6BCORHAT1EP300 | |
| SCHEMBL19984304 | 0.80 | NR4A2 (0.38) | NR4A2RAB9AHAT1EP300MAPK14 | |
| SCHEMBL19983988 | 0.80 | POLB (0.38) | NR4A2BCL6BCORPOLBMAPK8 | |
| SCHEMBL19983834 | 0.78 | PRKAG1 (0.42) | NR4A2BCL6BCORPRKAB2PRKAG1 | |
| SCHEMBL19983947 | 0.75 | TUBB1 (0.48) | NR4A2PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL19983715 | 0.74 | HTR2A (0.42) | BCL6BCORMAPK8MAPK10MAPK14 | |
| SCHEMBL22864436 | 0.72 | NR4A2 (0.63) | NR4A2RAB9ALMNA | |
| SCHEMBL19983934 | 0.72 | TUBB1 (0.41) | NR4A2 | |
| SCHEMBL30762247 | 0.71 | ALDH1A1 (0.51) | NR4A2 | |
| SCHEMBL10322039 | 0.70 | NR4A2 (0.60) | NR4A2PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |