Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984167 | 0.88 | NR3C1 (0.42) | CDK2NR3C1PGRNR3C2BCHE | |
| SCHEMBL19983711 | 0.87 | CDK2 (0.40) | CDK2NR3C1PGRNR3C2BCHE | |
| SCHEMBL19984116 | 0.84 | CDK2 (0.44) | CDK2NR3C1PGRNR3C2BCHE | |
| SCHEMBL19984005 | 0.75 | HTR2A (0.44) | NR3C1NR3C2MAPTSMN1; SMN2CHRNB2 | |
| SCHEMBL19983858 | 0.74 | GPR84 (0.40) | CFTRCHRNB2CHRNA7CHRNA4KCNH2 | |
| SCHEMBL19984003 | 0.74 | GPR84 (0.50) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983771 | 0.74 | CHRNB2 (0.38) | CFTRCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984124 | 0.74 | GPR84 (0.42) | CFTRMEN1KMT2ACHRNB2CHRNA7 | |
| SCHEMBL19984197 | 0.74 | GPR84 (0.49) | SLC6A4CHRNB2CHRNA7CHRNA4SLC6A3 | |
| SCHEMBL19983751 | 0.74 | GPR84 (0.40) | NR3C1CFTRMEN1KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |