Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983711 | 0.88 | CDK2 (0.40) | NR3C1NR3C2PGRCDK2SLC6A4 | |
| SCHEMBL19983952 | 0.88 | ABCC9 (0.40) | NR3C1NR3C2PGRCDK2SLC6A4 | |
| SCHEMBL19984005 | 0.86 | HTR2A (0.44) | NR3C1NR3C2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984116 | 0.85 | CDK2 (0.44) | NR3C1NR3C2PGRCDK2SLC6A4 | |
| SCHEMBL19983867 | 0.84 | HTR2C (0.42) | SLC6A4CHRNB2CHRNA7CHRNA4MEN1 | |
| SCHEMBL19984197 | 0.84 | GPR84 (0.49) | SLC6A4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983891 | 0.84 | GPR84 (0.49) | NR3C1SLC6A4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19984215 | 0.82 | GAA (0.47) | CDK2MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL19983847 | 0.82 | TBXAS1 (0.42) | NR3C1NR3C2CDK2SLC6A4CHRNB2 | |
| SCHEMBL19983944 | 0.80 | GPR84 (0.40) | NR3C1CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |