Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983978 | 0.89 | MTNR1A (0.35) | MTNR1AMTNR1BHTR2ASLC6A4KCNH2 | |
| SCHEMBL19984040 | 0.88 | MTNR1A (0.34) | MTNR1AMTNR1BHTR2ASLC6A4KCNH2 | |
| SCHEMBL19984212 | 0.83 | SLC6A4 (0.33) | HTR2ASLC6A4KCNH2KDM4EHPGD | |
| SCHEMBL16626655 | 0.82 | RORC (0.39) | HSP90AA1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL16618977 | 0.82 | RORC (0.39) | HSP90AA1CNR2 | |
| SCHEMBL19983942 | 0.80 | KDM4E (0.31) | SLC6A4KDM4EHPGDXBP1 | |
| SCHEMBL19984219 | 0.76 | SLC6A2 (0.36) | SLC6A4P2RX7 | |
| SCHEMBL19984020 | 0.75 | MTNR1A (0.33) | MTNR1AMTNR1BP2RX7 | |
| SCHEMBL19983902 | 0.75 | MTNR1A (0.33) | MTNR1AMTNR1BSLC6A4KCNH2P2RX7 | |
| SCHEMBL19984289 | 0.74 | NR1I2 (0.39) | MTNR1AMTNR1BSLC6A4KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |