Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984040 | 0.92 | MTNR1A (0.34) | MTNR1AMTNR1BSLC6A4KCNH2HTR2A | |
| SCHEMBL19983971 | 0.89 | PDE5A (0.33) | MTNR1AMTNR1BSLC6A4KCNH2HTR2A | |
| SCHEMBL19983902 | 0.85 | MTNR1A (0.33) | MTNR1AMTNR1BSLC6A4KCNH2SLC6A2 | |
| SCHEMBL16619196 | 0.80 | HTR6 (0.43) | MTNR1AMTNR1B | |
| SCHEMBL19984020 | 0.77 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL16619291 | 0.74 | HTR6 (0.43) | — | |
| SCHEMBL19983780 | 0.74 | PLK4 (0.30) | — | |
| SCHEMBL16626653 | 0.74 | HTR6 (0.40) | MTNR1AMTNR1BHTR2A | |
| SCHEMBL19983936 | 0.73 | TOP2A (0.32) | — | |
| SCHEMBL19984208 | 0.73 | SLC6A4 (0.34) | SLC6A4KCNH2HTR2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |