Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983978 | 0.92 | MTNR1A (0.35) | MTNR1AMTNR1BSLC6A4HTR2AKCNH2 | |
| SCHEMBL19983971 | 0.88 | PDE5A (0.33) | MTNR1AMTNR1BSLC6A4HTR2AKCNH2 | |
| SCHEMBL19983936 | 0.81 | TOP2A (0.32) | FGFR1FGFR4 | |
| SCHEMBL19983902 | 0.78 | MTNR1A (0.33) | MTNR1AMTNR1BKMT2ASLC6A4KCNH2 | |
| SCHEMBL19983901 | 0.77 | TSHR (0.35) | MEN1KMT2A | |
| SCHEMBL19984020 | 0.76 | MTNR1A (0.33) | MTNR1AMTNR1B | |
| SCHEMBL19983825 | 0.75 | CARM1 (0.32) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19984031 | 0.75 | ALDH1A1 (0.38) | FGFR1FGFR4 | |
| SCHEMBL19984299 | 0.75 | SLC6A4 (0.35) | MEN1KMT2ASLC6A4HTR2AKCNH2 | |
| SCHEMBL16619196 | 0.74 | HTR6 (0.43) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |