Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984219 | 0.87 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3NPC1APP | |
| SCHEMBL16619007 | 0.83 | HTR6 (0.42) | NR1I2PGRCHRM2ADORA3ADRA2C | |
| SCHEMBL19984057 | 0.80 | AKR1C3 (0.35) | NPC1KMT2AKDRAPPBRAF | |
| SCHEMBL19984020 | 0.78 | MTNR1A (0.33) | MTNR1AMTNR1BEGFRP2RX7 | |
| SCHEMBL19983902 | 0.77 | MTNR1A (0.33) | NR1I2PGRCHRM2ADORA3ADRA2C | |
| SCHEMBL19983971 | 0.74 | PDE5A (0.33) | SLC6A4KCNH2MTNR1AMTNR1BKDM4E | |
| SCHEMBL19984022 | 0.71 | AKR1C3 (0.38) | GAAPOLBKDRAPPALDH1A1 | |
| SCHEMBL19983937 | 0.71 | MPO (0.37) | SLC6A2SLC6A4KCNH2POLBKMT2A | |
| SCHEMBL19984029 | 0.71 | APP (0.35) | SLC6A4PTGS2KCNH2EGFRAPP | |
| SCHEMBL19984021 | 0.71 | GAK (0.40) | SLC6A4KCNH2POLBKMT2AEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |