Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983936 | 0.86 | TOP2A (0.32) | — | |
| SCHEMBL19984212 | 0.85 | SLC6A4 (0.33) | KDM4EHPGDXBP1SLC6A2SLC6A4 | |
| SCHEMBL19983971 | 0.80 | PDE5A (0.33) | KDM4EHPGDXBP1SLC6A4 | |
| SCHEMBL16618774 | 0.80 | RORC (0.42) | HPGDALDH1A1 | |
| SCHEMBL19983937 | 0.73 | MPO (0.37) | KDM4EHPGDXBP1SLC6A2SLC6A4 | |
| SCHEMBL19984029 | 0.73 | APP (0.35) | SLC6A4 | |
| SCHEMBL19983825 | 0.72 | CARM1 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19984022 | 0.72 | AKR1C3 (0.38) | ALDH1A1 | |
| SCHEMBL19984182 | 0.72 | P2RX7 (0.31) | — | |
| SCHEMBL16619252 | 0.71 | HTR6 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |