Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984031 | 0.88 | ALDH1A1 (0.38) | CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL19983812 | 0.85 | CYP11B1 (0.38) | CYP11B2CYP11B1MAT2AALDH1A1 | |
| SCHEMBL19984127 | 0.84 | NUDT1 (0.36) | SLC6A4SLC6A2KCNH2CYP11B2CYP11B1 | |
| SCHEMBL16626650 | 0.79 | SLC6A4 (0.33) | SLC6A4SLC6A2KCNH2CYP11B2CYP11B1 | |
| SCHEMBL17971578 | 0.79 | HTR6 (0.41) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19983727 | 0.79 | ABL1 (0.36) | SLC6A4SLC6A2ALDH1A1LMNAHTR2C | |
| SCHEMBL19983733 | 0.79 | SLC6A2 (0.37) | SLC6A4SLC6A2CYP11B2CYP11B1MAOA | |
| Hydrochloric Acid SCHEMBL16618903 | 0.78 | HTR6 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL19983848 | 0.77 | MAP3K8 (0.32) | HTR2C | |
| SCHEMBL19983804 | 0.77 | EPHX2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |